Themes

Vectors around which our research is oriented.

Multiple measures of diagnosis and experience

Depression is many things, and is measurable in many ways. We are studying how the ascertainment of depression status influences results from genetic studies. We also consider heterogeneity in the aetiology and expression of depression.

Projects

Projects our members lead on.

Cardiometabolic and mental health

Hearts, minds, and what's inbetween

Investigation of gene clusters implicated in cardiometabolic diseases and mood disorders.

DATAMIND

The Health Data Research Hub for Mental Health

Reproducible workflows for molecular phenotyping and experimental medicine.

G-AIM

The Genetics of Anxiety In Malawi (G-AIM) Study

What is the molecular genetic basis of anxiety in a very-low-income African setting?

GenScot

Generation Scotland

Bioinformatics, genetic studies, multi-omics.

Collaborations

Other endeavours we work with.

AMBER

Antidepressant Medications: Biology, Exposure & Response

Undertaking genetic, informatic and cellular work to give insights into the “active ingredients” of anti-depressants and infer how these drugs can better be used to treat depression. Currently working on genetic studies of antidepressant exposure.

Life-Epi-Psych

Lifecourse epidemiology and psychiatry

Longitudinal modelling of psychiatric genetic data.

PGC

Psychiatric Genomics Consortium

Core analytics for the Major Depressive Disorder Working Group and contribution of MDD and ANX datasets.